이현태 교수님

lht

이 현 태  교수님

 

• 전   공 : 위장관 운동 생리학, 신약 개발
 
• 연락처 : 051-890-1534 (연구실)
 
• 이메일 : htlee@deu.ac.kr

 
 
 
<학위>
 

학사-서울대학교
석사-서울대학교
박사-서울대학교

 
<EXPERIENCES & ACTIVITIES>
 

Chairman (02/2012-present)

Department of Life Science & Biotechnology, College of Natural Sciences, Dong-eui University, Busan, Korea

Associate Editor (01/2011-present)

Editorial Board of Archives of Pharmacal Research; the Pharmaceutical Society of Korea, Seoul, Korea

Assistant Professor (09/2010-present)

Department of Life Science & Biotechnology, College of Natural Sciences, Dong-eui University, Busan, Korea

Full-time Lecturer (03/2009-08/2010)

Department of Life Science & Biotechnology, College of Natural Sciences, Dong-eui University, Busan, Korea

Research Assistant Professor (08/2008-03/2009)

Department of Physiology and Cell Biology, Universityof Nevada School of Medicine, Reno, Nevada

Postdoctoral Associate (09/2003-07/2008)

Department of Physiology and Cell Biology, Universityof Nevada School of Medicine, Reno, Nevada

Advisor: Dr. Kenton M. Sanders

Postdoctoral Associate (03/2001-10/2002)

Research Institute for Basic Sciences, EwhaWomansUniversity, Seoul, Korea

Advisor: Dr. Eun-Kyoung Seo

Research Associate (03/1998-02/2004)

ResearchCenterfor New Drug Development, SeoulNational University, Seoul, Korea

PEER-REVIEWED PUBLICATIONS (SCI)

1) Hyun-Tai Lee, Byung Joo Kim. 2011. Trimebutine as a modulator of gastrointestinal motility. Archives of Pharmacal Research 34(6): 861-864.

2) Grant W. Hennig, Nick J. Spencer, Sari Jokela-Willis, Peter O. Bayguinov, Hyun-Tai Lee, Laura A. Ritchie, Sean M. Ward, Terence K. Smith, Kenton M. Sanders. 2010. ICC-MY coordinate smooth muscle electrical and mechanical activity in the murine small intestine. Neurogastroenterology & Motility 22(5): e138-e151.

3) Sadeea Qureshi, Jangho Song, Hyun-Tai Lee, Sang Don Koh, Grant W. Hennig, Brian A. Perrino. 2010. CaM kinase II in colonic smooth muscle contributes to dysmotility in murine DSS-colitis. Neurogastroenterology & Motility 22(2): 186-195.

4) Won-Sik Shim, Heejung Back, Eun-Kyoung Seo, *Hyun-Tai Lee, *Chang-Koo Shim. 2009. Long-term administration of an aqueous extract of dried, immature fruit of Poncirus trifoliata (L.) Raf. suppresses body weight gain in rats. Journal of Ethnopharmacology 126(2): 294-299.

 
<Corresponding co-authors>
 
5) Hyun-Tai Lee, Grant W. Hennig, Kyu Joo Park, Peter O. Bayguinov, Sean M. Ward, Kenton M. Sanders, Terence K. Smith. 2009. Heterogeneities in ICC Ca2+ activity within canine large intestine. Gastroenterology 136(7): 2226-2236.

6) Eamonn J. Dickson, Grant W. Hennig, Dante J. Heredia, Hyun-Tai Lee, Peter O. Bayguinov, Nick J. Spencer, Terence K. Smith. 2008. Polarized intrinsic neural reflexes in response to colonic elongation. Journal of Physiology – London 586(17): 4225-4240.

7) Hyun-Tai Lee, Grant W. Hennig, Neal W. Fleming, Kathleen D. Keef, Nick J. Spencer, Sean M. Ward, Kenton M. Sanders, Terence K. Smith. 2007. Septal interstitial cells of Cajal conduct pacemaker activity to excite muscle bundles in human jejunum. Gastroenterology 133(3): 907-917.

8) Hyun-Tai Lee, Grant W. Hennig, Neal W. Fleming, Kathleen D. Keef, Nick J. Spencer, Sean M. Ward, Kenton M. Sanders, Terence K. Smith. 2007. The mechanism and spread of pacemaker activity through myenteric interstitial cells of Cajal in human small intestine. Gastroenterology 132(5): 1852-1865.

9) Nick J. Spencer, Peter Bayguinov, Grant W. Hennig, Kyu Joo Park, Hyun-Tai Lee, Kenton M. Sanders, Terence K. Smith. 2007. Activation of neuronal circuitry and Ca2+ waves in longitudinal and circular muscle during CMMCs and the consequences of rectal aganglionosis in mice. American Journal of Physiology – Gastrointestinal and Liver Physiology 292(2): G546-G555.

10) *Kyu Joo Park, *Grant W. Hennig, *Hyun-Tai Lee, Nick J. Spencer, Sean M. Ward, Terence K. Smith, Kenton M. Sanders. 2006. Spatial and temporal mapping of pacemaker activity in interstitial cells of Cajal in mouse ileum in situ. American Journal of Physiology – Cell Physiology 290(5): C1411-C1427.

 
<Equal contribution>
 
11) Hyun-Tai Lee, Eun-Kyoung Seo, Suk-Jae Chung, Chang-Koo Shim. 2005. Prokinetic activity of an aqueous extract from dried immature fruit of Poncirus trifoliata (L.) Raf. Journal of Ethnopharmacology 102(2): 131-136.

12) Hyun-Tai Lee, Eun-Kyoung Seo, Suk-Jae Chung, Chang-Koo Shim. 2005. Effect of an aqueous extract of dried immature fruit of Poncirus trifoliata (L.) Raf. on intestinal transit in rodents with experimental gastrointestinal motility dysfunctions. Journal of Ethnopharmacology 102(2): 302-306.

13) Kang-Hoon Je, Ah-Reum Han, Hyun-Tai Lee, Woongchon Mar, Eun-Kyoung Seo. 2004. The inhibitory principle of lipopolysaccharide-induced nitric oxide production from Inula britannica var. chinensis. Archives of Pharmacal Research 27(1): 83-85.

14) Woongchon Mar, Hyun-Tai Lee, Kang-Hoon Je, Hye-Young Choi, Eun-Kyoung Seo. 2003. A DNA strand-nicking principle of a higher plant, Caesalpinia sappan. Archives of Pharmacal Research 26(2): 147-150.

15) Hyun-Tai Lee, Suk-Jae Chung, Chang-Koo Shim. 2002. Small intestinal transit does not adequately represent postoperative paralytic ileus in rats. Archives of Pharmacal Research 25(6): 978-983.

16) Hyun-Tai Lee, Seung-Won Yang, Kyeong Ho Kim, Eun-Kyoung Seo, Woongchon Mar. 2002. Pseudoguaianolides isolated from Inula britannica var. chinensis as inhibitory constituents against inducible nitric oxide synthase. Archives of Pharmacal Research 25(2): 151-153.

17) Hyun-Tai Lee, Young-Joo Lee, Suk-Jae Chung, Chang-Koo Shim. 2000. Effect of prokinetic agents, cisapride and metoclopramide, on the bioavailability in humans and intestinal permeability in rats of ranitidine, and intestinal charcoal transit in rats. Research Communications in Molecular Pathology and Pharmacology 108(5-6): 311-323.